Interaction of Chelating Agents with Cadmium in Mice and Rats

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Interaction of chelating agents with cadmium in mice and rats.

The influence of several chelating agents (CaDTPA, ZnDTPA, CaEDTA, ZnEDTA, DMSA, D-penicillamine and DMPS, DMP and DDC) on the acute toxicity of CdCl2 and on the whole body retention and tissue distribution of cadmium after the IV application of 115mCdCl2 was compared in mice. The chelating agents were applied immediately after the application of cadmium. CaDTPA, ZnDTPA and DMSA appeared to be ...

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Symptoms and signs in humans after excessive exposure to cadmium usually involve the gastrointestinal tract after single oral intake, the lung after acute inhalation, and the kidney after long-term exposure. These organs are usually considered to be the "critical" organs, i.e., the organs most sensitive at a certain type of exposure. The type of Cd-related damage that is most common in humans i...

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study of dna interaction with ethylenediaminetetraacetic acid and sesamol food additives

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15 صفحه اول

Alteration of tissue disposition of cadmium by chelating agents.

The effect of several chelating agents (diethyldithiocarbamic acid, DDC; nitrilotriacetic acid, NTA; 2,3-dimercaptopropanol, BAL; d,l-penicillamine, PEN; 2,3-dimercaptosuccinic acid, DMSA; ethylenediaminetetraacetic acid, EDTA; and diethylenetriaminepentaacetic acid, DTPA) on the toxicity, distribution and excretion of cadmium (Cd) was determined in mice. When chelators were administered immedi...

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Enhanced electrokinetic remediation of cadmium contaminated soils by chelating agents

Electrokinetic soil remediation by electroosmosis and ionic migration is restricted to soluble substances. At a higher pH, the soil particles sorb more heavy metals than at a lower pH and the precipitation reactions of heavy metals are promoted. Both mechanisms make heavy metals immobile, rendering cleanup more difficult and electrokinetic extraction inefficient. In this study, the effectivenes...

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ژورنال

عنوان ژورنال: Environmental Health Perspectives

سال: 1984

ISSN: 0091-6765

DOI: 10.2307/3429814